SUSL Staff Directory

Dr. N.D.Amal Wageesha

Position: Senior Lecturer

awageesha@med.sab.ac.lk

Qualifications

PhD in Biochemistry (Cancer Metabolism)

University of Colombo.

Sri Lanka

 

MPhil in Biochemistry (Nutritional Biochemistry)

University of Sri Jayewardenapura.

Sri Lanka

 

Graduateship in Chemistry

Institute of Chemistry Ceylon,

Sri Lanka


Membership of Professional Bodies/Associations

  • Vice Precedent/Committee member Science Popularization committee, Sri Lanka Association for Advancement of Science (SLAAS/CPS).
  • Member of the Sri Lanka Association for the Advancement of Science (SLAAS).
  • Member of Young Scientist Forum, Sri Lanka (YSF).
  • Member of the Institute of Chemistry Ceylon (M IChem C).
  • President, Alumni Association of College of chemical Sciences, Institute of chemistry Ceylon (2017-2018).

Research Interests

Identifying and charecterization of novel anti cancer drugs based on traditional medicne


Recent Publications

     

Wageesha N.D.A, P, Soysa, AAP Keerthi, I Choud hary and M Ekanayake (2017).

The Polyherbal traditional medicinal drug “Le Pana Guliya” Induces Apoptosis in Human Cancer through GSH depletion, ROS production and mitochondrial dysfunction: An In vitro assessment. Chemistry Central Journal. 11:2 DOI 10.1186/s13065-016-0234-4

           

            Wageesha N.D.A, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2017).

Evaluation of antioxidant and polyphenolic content of a Sri Lankan poly herbal formulae and assessment of its in vitro antiproliferative activity on RD and MCF-7 cancer cells compared to healthy CC1 cells. Cancer Studies and Therapeutics Journal. 2 (3):1-8.

 

Wageesha N.D.A, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2018).

A Traditional Poly Herbal Drug Induced Apoptosis via Caspase 3 Mediated Pathway in RD Cells but Caspase 3 Independent Pathway in MCF-7 Cells. Asian Journal of Ethnopharmacology and Medicinal Foods 4 (2) : 17-25.


Research Publication in Indexed Journals

Wageesha, N.D.A, Ekanayake, S, Jansz, E.R. and Lamabadusuriya, S.P (2010).

“Studies on hypercarotenemia due to excessive ingestion of carrot, pumpkin and papaw” International Journal of Food Science and Nutrition. http://informahealthcare.com/doi/abs/10.3109/09637486.2010.511164

 

Wageesha, N.D.A, Ekanayake, S, Jansz, E.R. and Lamabadusuriya, S.P (2010).

“Effect of feeding excessive carrot and papaw to Wistar rats and ICR mice to induce hypercarotenaemia” Vidyodaya Journal of Science 15: 27-35.

 

Wageesha, N.D.A, Ekanayake, S, Jansz, E.R. and Lamabadusuriya, S.P (2013).

Prevalence of hypercarotenaemia in nursery/kindergarten children in the Western province in Sri Lanka: A preliminary survey". International Food Research Journal 20(4): 1873-1875

 

      Wageesha N.D.A, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2017).

The Polyherbal traditional medicinal drug “Le Pana Guliya” Induces Apoptosis in Human Cancer through GSH depletion, ROS production and mitochondrial dysfunction: An In vitro assessment. Chemistry Central Journal. 11:2 DOI 10.1186/s13065-016-0234-4

 

            Wageesha N.D.A, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2017).

Evaluation of antioxidant and polyphenolic content of a Sri Lankan poly herbal formulae and assessment of its in vitro antiproliferative activity on RD and MCF-7 cancer cells compared to healthy CC1 cells. Cancer Studies and Therapeutics Journal. 2 (3):1-8

 

Wageesha N.D.A, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2018).

             A Traditional Poly Herbal Drug Induced Apoptosis via Caspase 3 Mediated Pathway in RD Cells but Caspase 3 Independent Pathway in MCF-7 Cells.           Asian Journal of Ethnopharmacology and Medicinal Foods 4 (2) : 17-25


Published in abstract/Extended abstract at the National/International Conferences/Symposium

            Wageesha, N.D.A, Jayawardene, M.I.F.P. and Ruvinkumara, N.K.V.M (2008).

“Preliminary investigation on Anti-Hypercholesterolemic effect of Olax Zeylanica on Wistar rats” First Research Sessions College of Chemical Sciences, Institute of Chemistry Ceylon.

 

Wageesha, N.D.A, Ekanayake S, Jansz, E.R. and Lamabadusuriya, S.P. (2008).

“Recognition of foods responsible for Hypercarotenaemia from serum metabolic profiles” Sri Lanka Association for the Advancement of Science 64th Annual sessions.

 

             Wageesha, N.D.A, Ekanayake S, Jansz, E.R. and Lamabadusuriya, S.P. (2008).

“A preliminary investigation on prevalence of hypercarotenaemia among infants/children in the Western province” The College of General Practitioners of Sri Lanka, 35thAnnual Academic Sessions.

 

Wageesha, N.D.A, Ekanayake S, Jansz, E.R. and Lamabadusuriya, S.P. (2008).

“Fate of excess carotenoids fed to Wistar rats and ICR mice” Sri Lanka Association of Advancement of Science 65th Annual session.

 

Wageesha, N.D.A, Ekanayake, S, Jansz, E.R. and Lamabadusuriya, S.P. (2009).

“Vitamin A mega dosing and development of hypercarotenaemia” 50th Anniversary Academic conference, University of Sri Jayewardenepura.

 

            Wageesha, N.D.A, Ekanayake, S, Jansz, E.R. and Lamabadusuriya, S.P. (2009).

Development of Hypercarotenaemia: Loss of control over absorption of pro-vitamin A Carotenoids? Annual Academic Sessions Nutrition Society 2011.

 

            Wageesha, N.D.A, P, Soysa and AAP Keerthi (2014).

Screening of two medicinal plant extracts for Anti-Oxidant Capacity and Total phenolic Content. International Conference on Chemical Education. College of Chemical Sciences, Institute of Chemistry Ceylon.

 

            Wageesha, N.D.A, P, Soysa AAP Keerthi, IChoudhary and M Ekanayake. (2015).

Screening of Anti-Cancer Activity of a Poly herbal drug used in traditional medicinal practice. 8th International Research conference (IRC-8). Inculcating Professionalism for National Development. General Sir John Kotelawala Defense University.

 

            Wageesha, N.D.A, P, Soysa AAP Keerthi, I Choudhary and M Ekanayake (2015).

Anti-proliferative activity of aqueous extract of the “Le Pana Guliya”, A scientific insight. National Conference on Indigenous Systems of Medicine .Research and Innovations in Indigenous Systems of Medicine for 21st Century. Bandaranaike Memorial Ayurvedic Research Institute.

 

Wageesha, N.D.A, P, Soysa AAP Keerthi, I Choudhary and M Ekanayake (2015).

Intrinsic anti cancer effects of aqueous extract of poly herbal drug named “Le Pana guliya” on HepG2 and RD cells. 3rd International conference on Ayurveda, Unani, Siddha and Traditional medicine 2015. Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka.

 

Wageesha NDA, P, Soysa AAP Keerthi, I Choudhary and M Ekanayake (2017).

Traditional anti cancer drug “Le Pana Guliya” induced oxidative stress via depletion of Reduced Glutathione; An in vitro assessment. 4th Hamdard International conference on Unani medicine 2017, Karachi, Pakistan.

 

Wageesha NDA, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2017).

Evaluation of anti proliferative activity and mechanism of action of a polyherbal drug formulation used in traditional medicine for cancer therapy. 7th International Conference on Ayurveda, Homeopathy and Chinese Medicine, Munich Germany.

 

Wageesha NDA, P, Soysa, AAP Keerthi, I Choudhary and M Ekanayake (2017).

Evaluation of antiproliferative activity of a polyherbal drug formulation used in traditional medicine for cancer therapy. 10th Annual World Cancer Congress (WCC-2017), Barcelona, Spain.

 

            Wageesha N.D.A, P, Soysa, AAP, Keerthi, I, Choudhary and M, Ekanayake (2017).

Evaluation of antioxidant and polyphenolic content of a Sri Lankan poly herbal formulae and assessment of its in vitro antiproliferative activity and mechanism of action on RD and MCF-7 cancer cells compared to healthy CC1 cells. 3rd International Conference and Expo on Herbal and Alternative Medicine, London, United Kingdom.