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Professor MN Wickramaratne

Professor

Applied Sciences

Email : nirmaliw@appsc.sab.ac.lk

Mobile :0714468733

Office : 0452280013

Fax : 0452280013

    Qualifications

  • Ph.D. in Biochemistry

    Loyola University, Chicago

    Chicago, Illinois USA

     

    Graduate in Chemistry

    Institute of Chemistry Ceylon Rajagiriya

    Sri Lanka

    Membership of Professional Bodies/Associations

  • Life Member, Sri Lanka Association for the Advancement of Science.

    Life Member, Institute of Chemistry Ceylon

    Research Interests

  • Protein -Drug Interaction (investigation on protein denaturation and Drug-Protein binding capacities under varying buffer conditions

    Impact of energy balance and physical activity changes on body composition and physical fitness during the university years of Sports Sciences undergraduates in Sri Lanka

    Preparation of Hydroxyapatite nano-composites for biomedical applications

    Antioxidant and anti-diabetic activities of medicinally important plants in Sri Lanka

    Genetic analysis of β Thalassemia mutations

    Research Interests

    Current Research Projects

  • Protein -Drug Interaction (investigation on protein denaturation and Drug-Protein binding capacities under varying buffer conditions

    Impact of energy balance and physical activity changes on body composition and physical fitness during the university years of Sports Sciences undergraduates in Sri Lanka (Funded by Sabaragamuwa University Research Grant)

    Preparation of Hydroxyapatite nano-composites for biomedical applications (Research Collaboration with Prof Yingchao Han ,Wuhan University of Technology China)

    Antioxidant and anti-diabetic activities of medicinally important plants in Sri Lanka (With the Collaboration of Prof D.B. Mahinda Wickramaratne Faculty of Allied Health Sciences and Prof Lalith Jayasinghe Institute of Fundamental Studies Hanthana Kandy)

    Recent Publications

  • Ultrasound-Assisted Synthesis and Characterization of Heparin-Coated Eu3+ Doped Hydroxyapatite Luminescent Nanoparticles Qingguo Xing, Xiaojun Zhang, Dulan Wu, Yingchao Han, M.Nirmali Wickramaratne Honglian Dai Xinyu Wang, Colloid and Interface Science Communications 29 (2019) 17–25

    Controllable Synthesis of Poly(acrylic Acid)-Stabilized Nano-Hydroxyapatite Suspension by an Ultrasound-assisted Precipitation Method Dong Yan, Yuxin Lou, Yingchao Han, M. Nirmali Wickramaratne, Honglian Dai, Xinyu Wang 2018 Materials Letters: 4, 124 - 227
     

    Influence of alginate fixation on the adsorption capacity of hydroxyapatite nanocrystals to Cu2+ ions, Jiali Guo, Yingchao Han, Yuting Mao, M. Nirmali Wickramaratne, Colloids and Surfaces A, 2017; 529, 801–807

    Screening of edible plants in Sri Lanka for antioxidant activity. Chethana Galketiya T Sampath Weerarathna, J Chamini Punchihewa M Nirmali Wickramaratne and DBM Wickramaratne, Journal of Medicinal Plants Studies, 2017 5(1) 91-95

    Hemoglobin Denaturation in the Presence of Chloroquine Phosphate. S. M. Soysa, M. Nirmali Wickramaratne. J Pharm Chem Biol Sci, 2016; 4 (4)

    Contamination of Heavy Metals in Aquatic Vegetables Collected from Cultivation Sites in Sri Lanka. M. Nirmali Wickramaratne, L.L. Sanjaya, T. M. Maduranga IOSR Journal of Environmental Science, Toxicology and Food Technology, 2016, 10(11) 76-82

    In-vitro alpha amylase inhibitory activity of the leaf extracts of Adenanthera pavonina,M. Nirmali Wickramaratne J. C. Punchihewa and D. B. M. Wickramaratne, BMC Complementary and Alternative Medicine 2016, 16; 466-471

    Antioxidant Activity and Antibacterial Activity of Walidda antidysenterica. M. Nirmali Wickramaratne, L.P. Gunatilake, N.G. D. Anuradha, A.N. Godavillathanna, M.G.N. Perera, I. Nicholas., Journal of Pharmacognosy and Phytochemistry 2015; 4(2): 121-126

    Rare Haemoglobin Varients Hb G Szuhu and Hb G Coushatta and Hb Mizuho in Sri Lankan families P.S. Perera, D.P.S.I. Silva, M. Hapugoda, M.N. Wickramaratne, I. Wijesiriwardena, D.G. Efremove, C.A. Fisher, D.J. Weatherall, Anuja Premawardhena Hemoglobin (2015) 39: 1 62-65

    Completed Research Projects

  • Genetic analysis of β Thalassemia mutations (with the collaboration of Professor Sir David Weatherall of Weatherall Institute of Molecular Medicine at John Radcliffe Hospital, Oxford University and Prof. Anuja Permawardhena from University of Kelaniya Sri Lanka.)