SUSL Staff Directory

Dr. MAGAMAGE Manjula P Sumith

Senior Lecturer

magamage@agri.sab.ac.lk

Qualifications

  • BVSc (Sri Lanka), 2000
  • MSc (Kobe-Japan), 2008
  • PhD (Kobe-Japan), 2011
  • Fulbright Acadamic and Research Fellow- University of Nebraska Lincoln, USA, 2013/14
  • Indian Science Research Fellow- National Institute of Animal Biotechnology, Hyderabad, India 2016/17
  • Eendeavour Research Fellow- ANZAC Clinical and Medical Research Institute, Concord General Hospital, University of Sydney, Australia 2017
  • Consultant Veterinary Surgeon-Gynaecology,Obstetrics,,Endocrinology and Assisted Reproductive Technology.
  • Fellow of Sri Lanka College of Veterinary Surgeons, Sri Lanka Veterinary Council 1077
  • Accredited University Teacher in Sri Lanka Higher Education/University Grants Commission Completed in Year 2004
  • Endeavour Awards Ambassador, Government of Australia, Department of Education and Training, Australian High Commission, 1/50G Shanthipath, Chanakyapuri, New Delhi, India.

Profile

Manjula P Sumith Magamage received his Bachelor in Veterinary Medicine and Animal Science (BVSc) degree from Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Sri Lanka in 2000 and his Masters and PhD in Reproductive Physiology, Endocrinology and Reproductive Biotechnology from the Department of Bioresource Production, Faculty of Graduate Studies, and University of Kobe, Japan in 2011. Following his doctoral studies followed by his post-doctoral training in Reproductive Physiology/Cell, Molecular Biology and Biotechnology at the University of Nebraska Lincoln, USA under mentorship of Professor Andrea S Cupp in 2013-2014. Later he was awarded Indian Science Research Fellowship in 2016 from Government of India where he was in National Institute of Animal Biotechnology at Hyderabad. Early 2017, Government of Australia was awarded him most prestigious Endeavour Fellowship and was at ANZAC Research Institute at Concord General Hospital, University of Sydney, Australia. He joined to the Department of Livestock Production, Faculty of Agricultural Sciences at Rahangala Campus in year 2001 as Assistant Lecturer in Livestock Production after spent brief spell at Department of Clinical Studies, Faculty of Veterinary Medicine, University of Peradeniya in 2000 and and subsequently promoted to the post of Lecturer (Probationary) in 2003 at Belihuloya Campus followed by his graduate studies in Japan from 2005-2011 until he back to Department of Livestock Production as Senior Lecturer in 2011.Curretnly he is teaching both undergraduate and graduate students of the faculties of Agricultural Sciences as well as Faculty of Graduate Studies. He was the founder coordinator for Faculty of Health and Medical Sciences and currently served as a member of the steering committee of Faculty of Medicine of Sabaragamuwa University. Apart from these interdepartmental commitments his teaching and research are widely perceived on human -animal interface studies. Major areas of the current teaching are comprised on Anatomy and Physiology farm animals, Animal Health, Reproductive Biology and Biotechnology and Biochemistry. Kisspeptin role in HPG axis on Mammalian fertility, Androgen effect on female gonad, Developmental impact of androgen on fertility management and life expectancy in mice and rats, Implications of vascular endothelial growth factor A (VEGFA) regulation of mammalian primordial follicle development in vitro, Proteomic and Genomic alterations during mammalian oocyte and granulosa cells coordination, Designing for alternative animal models for translation medicine are among the main research interests. He has been also trained at Marine Biological Laborotaroy (MBL), Boston, USA for Advanced biochemistry, Reproductive Biotechnology and Molecular Biology under Frontiers in Reproduction Programme (FIR) in 2016 summer programme. MBL is the most famous and renowned research laboratory in the world that more than 60 Nobel laureates working under same roof since it’s inception. Recently he has been appointed as Head of the Department of Livestock Production of Sabaragamuwa University.


Membership of Professional Bodies/Associations

Membership in Professional Societies

  • Since 2009 Member: Society for Study of Reproduction (SSR), Washington D.C ,USA.
  • Since 2002 Member: Sri Lanka Veterinary Association (SLVA), Sri Lanka.
  • Since 2004 Member: Sri Lanka Association of Animal Production (SLAAP), Sri Lanka.
  • Since 2012 Life member of Sri Lanka Association of Laboratory Animal Science, Faculty of Medicine, Department of Physiology, University Colombo
  • Since 2016 Life Member: Sri Lanka Association of Advancement of Science (SLAAS)Sri Lanka.
  • Since 2017 Member: Japanese Society of Animal Science (JSAS), Tokyo, Japan

Current Research Projects

  • On Going Collaborative Research Projects Under the External Funding- Outside of Sri Lanka
    • Kisspeptin role in regulation of VEGF165a and b in goat ovaries in vitro- National Institute of Animal Biotechnology, India. Principle Investigator: Dr. Sathya Velmurugan, Scientist C, NIAB, Hyderabad, India
    • Effect of DHT implants in regulation of reproductive axis of ARKO and WT mouse model in vivo- ANZAC Research Institute, Australia- Principle Investigators Professor David J. Handelsman University of Sydney, ANZAC Research Institute, Concord General Hospital. Concord, Sydney, Australia. Dr. Kirsty Walters, Senior Lecturer, University of New South Wales, NSW, Australia.
    • Effect of subcutaneous DHT implants in muscle mass of male WT mice. ANZAC Research Institute, Australia- Principle Investigators Professor David J. Handelsman University of Sydney, ANZAC Research Institute, Concord General Hospital. Concord, Sydney, Australia. Dr. Kirsty Walters, Senior Lecturer, University of New South Wales, NSW, Australia.
    • Effect of angiogenic and antiangiogeneic VEGFA 165 in regulation of follicle health under varying steroidal levels. Principle Investigators Professor Andrea S Cupp, University of Nebraska Lincoln, USA, Co Investigators, Robert (Bob) Cushman, USDA, USMARC, Clay center, Nebraska, USA.
  • On Going Research Projects with External Funding- Sri Lanka
    • SUSL/RG/2015/ 06 Effect of Pro and Anti Angiogenic Vascular Endothelial Growth Factor Isoform in follicular progression in bovine ovarian cortical pieces cultured from pre-pubertal heifers, 2015-2016-2 Years
    • NSF/2015/SCH/07 Effect of Vascular Endothelial Growth Factor A 165 (VEGFA165), Angiogenic Isoform and anti angiogenic VEGFA165b in follicular progression in procine ovarian. 2015-2018-3 years

Recent Publications

 

  1. R Vimonish, G H Galhena, K. L.N. Perera, M P S Magamage (2018). PCR Based Approach for Detection of Bovine Babesiosis in Suspected Carrier Cattle and Vector Ticks in Sri Lanka. Journal of Agricultural Sciences. 13(1), pp.55–65. DOI:http://doi.org/10.4038/jas.v13i1.8300

  2. DNN Madushanka, HMS Padmakumara, GDN Kumarasinghe, MPK Sanjeewa, MPS Magamage (2017). Effect of two different bedding systems on udder health management of dairy cows. Accepted Manuscript 2017 July; Ruminant Science Vol.6 No 1;Pagexxx-xxx 2017 

  3. Madushanka, DNN, Ranasingha, VM, Bandara,AMS, Mayurawansha WRAS, Magamage,MPS  (2017). Body condition score and locomotion score help to predict reproductive and health performances of dairy cattle reared under the intensive management system. Ruminant Science Vol.5 No 2;Page179-186 2016 Dec   https://www.researchgate.net/publication/317644506_8-346_DNN_Madushanka_Printed_Version
  4. R. Kirupananthan, L.C.J. Kramral , G.H. Galhena, K.L.N. Perera and M.P.S. Magamage Addressing the public Health and Food Security Concerns of Babesiosis through Molecular Detection of Babesia bovis in suspected carrier cattle of selected localities in Sri Lanka. Procedia Food Science 6 (2016 Sep ) 213 – 219. http://www.sciencedirect.com/science/article/pii/S2211601X16000547
  5. Manjula P. S. Magamage, Mai Zengyo, Mohammad Moniruzzaman, Takashi Miyano. 2011.Testosterone induces activation of porcine primordial follicles in vitro. Reprod. Med.Biol.,10, 21-30.Online access: http://rd.springer.com/article/10.1007/s12522-010-0068-z
  6. Magamage MPS •Mohammad Moniruzzaman • Takashi Miyano. 2011. Effect of KIT ligand on the viability of porcine primordial follicles in vitro. J. Mamm. Ova Res., 28, 61-67. http://www.bioone.org/doi/abs/10.1274/jmor.28.61?journalCode=jmor http://dx.doi.org/10.1274/jmor.28.61
  7. R M. A. S. Banadara, Manjula P. S. Magamage, T. S Samarakoon, Missaka P.B. Wijewardhana.Analysis of behaviour, growth and haematological parameters to determine the best weaning age in New Zealand White rabbit kits and does under tropical climatic conditions. Re-revised Manuscript is Pending.
  8. W.R.A.S.Mayurawansa, Viraj Ranasinghe, MPS Magamage. Characterization of Repeat Breeder cows based on Body Condition Score, Locomotion Score in Up Country Large Multiplier Farms in Sri Lanka, Journal of Ruminant Science December 2016, Submitted, Accepted with minor corrections.
  9. Manjula P. Sumith Magamage, Racheal G. Slattery, Kevin Sergent, Reneta S. Gomes, Willam E. Pohlmeier, Scott G. Kurz, Adam F. Summers, Renee McFee, Robert A. Cushman, Jennifer R. Wood, Andrea S. Cupp. Implications of VEGFA Isoforms on Follicular Development of the Rat Ovary In Vitro. Manuscript in preperation for Biology of Reproduction.
  10. Manjula P. Sumith Magamage, Ravali Sathyagopalan, Kiran Avula Yadave, DNN Madushanka and Sathya Velmurugan. Kisspeptin Regulate primordial follicle developemnt in goat ovaries in vitro. Manuscript  submited to Animal Reproduction Science. Under review.
  11. Manjula P. Sumith Magamage, Sathya Velmurugan. Implications of KISS 10 on Regultion of Ovarian Vasculature. Manuscript in Preparation, intended to submit Journal of Sterility and Fertility

Research Communications: In International Meetings

  1. Abedal-Majed Mohamed A, L. Hart Mariah, Largen Valerie, Magamage Manjula PS, Kurz Scott G, Sargent Kevin M, Bergman Jeffrey, McFee Renee M, Cushman Robert A, Davis John S, Wood Jennifer R, Cupp Andrea S. Ovarian Cortex from High A4 Cows Secretes Excess A4, and Exhibits Increased Oxidative Stress, Macrophage Markers and Arrested Follicle Development Which can be Partially Rescued by Angiogenic VEGFA (2017). SSR 50th Annual Meeting 2017, Washington DC, 15th 21st July 2017. https://www.xcdsystem.com/SSR/program/Mc7RXGm/index.cfm?pgid=923&search=1&qtype=speaker&speakerid=239103&submit=Go
  2. Ranasingha, VM, Madushanka, DNN, Bandara,AMS, Magamage,MPS (2017). Body Condition Score and Locomotion Score Help to Predict Reproductive and Health Performances of Dairy Cattle Reared Under the Intensive Management System in Sri Lanka. Symposium, Proceedings January 19th 2017, Pages 215-17, International Symposium on Agriculture and Environment 2017, University of Ruhuna, Sri Lanka.
  3. Madushanka, DNN Padmakumara, HMS, Kumarasinghe, GDN,. Sanjeewa, MPK, Magamage, MPS (2017). Effect of Two Different Bedding Systems on Udder Health Management of Dairy Cows. . Symposium, Proceedings January 19th 2017 Pages 208-10, International Symposium on Agriculture and Environment 2017, University of Ruhuna, Sri Lanka
  4. Muthumala N, Mayurawansha WRAS, Gunawardhana IBWL,Magamage MPS (2017). Postpartum Performance of Dairy Cows in Response to Body Condition Score, Locomotion Score, Suckling and Postpartum Diseases in Up Country Large Farm in Sri Lanka. . Symposium, Proceedings January 19th 2017 Pages 211-14, International Symposium on Agriculture and Environment 2017, University of Ruhuna, Sri Lanka
  5. Mohamed A. Abedal-Majed 1, Manjula Magamage3, Rebecca Vinton1, Scott G. Kurz1, Anthony K. McNeel2, Harvey C. Freetly2, Robert A Cushman2, Jennifer R. Wood1, Andrea S. Cupp* Effect of diet on ability of Vascular Endothelial Growth Factor A (VEGFA) isoforms to alter follicular progression in bovine ovarian cortical cultures. ID 336, SSR 2016 49th Annual Meeting of Society for Study of Reproduction, San Diego, USA 16-20 July 2016.https://www.researchgate.net/publication/281591436_Vascular_Endothelial_Growth_Factor_A_165_VEGFA165_Angiogenic_Isoform_promotes_while_VEGFA165b_antiangiogenic_isoform_antagonizes_VEGFA165_stimulated_follicular_progression_in_bovine_ovarian_cortical_p
  6. Manjula P. Sumith Magamage, Brizett D. Cole , Rebecca Vinton, William E. Pohlmeier, Scott G. Kurz1, Adam F. Summers1, Renee McFee1, Robert A. Cushman2, Jennifer R. Wood, Andrea S. Cupp. Expression of Vascular Markers in The Bovine Ovarian Cortex From Cows With Differing Steroidogenesis. FIR Symposium 10th June 2016, Marine Biological Laboratory, Woods Hole, MA, USA,. 9-11h June 2016.
  7. R.Kirupananthan, L.C.J. Kramral , G.H. Galhena, K.L.N. Perera and M.P.S. Magamage. Addressing the public Health and Food Security Concerns of Babesiosis through Molecular Detection of Babesia bovis in suspected carrier cattle of selected localities in Sri Lanka; 5th Annual Research Sessions Sabaragamuwa University of Sri Lanka; Proceedings (page 19) ARS 2015, Belihuloya, Sri Lanka, Sri Lanka 17th February 2016.
  8. R. Kirupananthan, L.C.J. Kramral , G.H. Galhena, K.L.N. Perera and M.P.S. Magamage Molecular Detection of Babesia bovis in suspected carrier cattle of selected localities in Sri Lanka; 5th International Conference of Sabaragamuwa University of Sri Lanka; Proceedings (page 17) ICSUSL 2015 Challenges Beyond Food Security, Colombo, Sri Lanka 19-20th November 2015. https://www.researchgate.net/search.Search.html?type=publication&query= Babesia+bovis%2C+Sri+lanka
  9. Mohamed Ayoub1, Manjula Magamage3, Rebecca Vinton1, Robert A Cushman2, Anthony K. McNeel2, Harvey C. Freetly2, Jennifer R Wood1, Andrea S Cupp Vascular Endothelial Growth Factor A 165 (VEGFA165), Angiogenic Isoform, promotes while VEGFA165b antagonizes VEGFA165 stimulated follicular progression in bovine ovarian cortical pieces cultured from pre-pubertal heifers. Biol Reprod June 02, 2015 (1 Supplement page 246) Abstract: 619, 48th Annual Meeting of the Society for the Study of Reproduction (SSR), San Juan, Puerto Rico, USA from 18–22 June 2015.https://www.researchgate.net/search.Search.html?type=publication&query=Babesia+bovis%2C+Sri+lanka
  10. Manjula P. Sumith Magamage, Brizett D. Cole , Rebecca Vinton, William E. Pohlmeier, Scott G. Kurz1, Adam F. Summers1, Renee McFee1, Robert A. Cushman2, Jennifer R. Wood, Andrea S. Cupp. Expression of Vascular Markers in The Bovine Ovarian Cortex From Cows With Differing Steroidogenesis; New Dimensions for Study Human Diseases through the Animal Disease Models (2014). One Health International Conference, Kandy, Sri Lanka. 5-6th September 2014.https://www.researchgate.net/search.Search.html?type=publication&query=Babesia+bovis%2C+Sri+lanka
  11. Brizett D. Cole, Manjula Magamage, Rebecca Vinton, William E. Pohlmeier, Scott G. Kurz, Adam F. Summers, Renee McFee, Robert A. Cushman, Jennifer R. Wood, Andrea S. Cupp. Expression of Vascular Markers in the Bovine Ovarian Cortex from Cows with Differing Steroidogenesis (2014). UCARE- Undergraduate creative and Research Symposium, University of Nebraska, Lincoln, USA. 16th April 2014.
  12. Rebecca J. Vinton, Brizett D. Cole, Manjula Magamage, Mohamed Ayoub, Adam F. Summers William E. Pohlmeier, Scott G. Kurz, Renee M. McFee, Robert A. Cushman, Jennifer R. Wood, Andrea S. Cupp (2014). Effect of VEGFA Isoforms on Heifer Follicular Development Bovine Cortical Ovarian Cultures. UCARE- Undergraduate creative and Research Symposium, University of Nebraska, Lincoln, USA 16th April 2014.
  13. T. P. Wickramatunga, Manjula P. S. Magamage, S. B. Yapa. Effect of Saccharomyces cerevisiae as probiotic on growth performances of Jersey calves under intensive management. InSym2012 , Belihuloya, Sri Lanka, January 11th and 12th 2013
  14. R M. A. S. Banadara, Manjula P. S. Magamage, T. S Samarakoon, Missaka P.B. Wijewardhana.Analysis of behaviour, growth and haematological parameters to determine the best weaning age in New Zealand White rabbit kits and does under tropical climatic conditions, THE 15TH AAAP ANIMAL SCIENCE CONGRESS 26-29 NOVEMBER 2012 AT THAILAND
  15. Manjula P. S. Magamage, Takashi Miyano. Ex-vitro development of In vitro-activated oocytes from porcine primordial follicles. ISAE proceedings Page 81. International Symposium on Agriculture and Environment (ISAE) 2011, Matara, Sri Lanka, November 09th 2011.
  16. Manjula P. S. Magamage Porcine primordial follicle activation in vitro and role of Stem cell biology. Special Invited Speech, Research Forum of Stem Cell Biology, Faculty of Veterinary Medicine, University of Calgary, Alberta, Canada26th September 2011.
  17. Manjula P.S. Magamage, Takashi Miyano. KIT ligand promotes the viability but not activation of porcine primordial follicles in vitro. 16th International Conference on Biotechnology in Animal Reproduction (ICBAR), Kandy, Sri Lanka, from 04th-5th August 2011.
  18. Manjula P.S. Magamage, Takashi Miyano. Porcine primordial follicle activation in vitro.Annual Research Sessions 2011, Kobe University, Kobe, Japan, 15 February 2011.
  19. Manjula P.S. Magamage, Mai Zengyo, M. Moniruzzaman, Takashi Miyano, Testosterone Induces Porcine Primordial Follicle Development In Vitro. Biol Reprod June 15, 2009 81 (1 Supplement) 506, 42nd Annual Meeting of the Society for the Study of Reproduction (SSR), Pittsburgh, Pensylvania, USA, from 16–24 July 2009.
  20. Manjula P. S. Magamage, Takashi Miyano. Effect of steroidal hormones and KIT ligand on porcine primordial follicle development in vitro. Annual Research Sessions 2008, Kobe University, Kobe, Japan, 21 February 2008.

Research Communications: In Local Meetings

1. Manjula P. S. Magamage, Takashi Miyano. Development of oocytes from porcine primordial follicles in mouse kidney xenograft. Annual research Session, Proceedings Page 05. Second Annual Research Session of Sabaragamuwa University (ARS-SUSL) 2011, Belihuloya, Sri Lanka, December 02nd 2011.

2. R M. A. S. Banadara, Manjula P. S. Magamage, T. S Samarakoon, Missaka P.B. Wijewardhana. Analysis of behaviour, growth and haematological parameters to determine the best weaning age in New Zealand White rabbit kits and does under tropical climatic condition, Annual Research Session, Proceedings Page 11. Second Annual Research Session of Sabaragamuwa University (ARS-SUSL) 2011, Belihuloya, Sri Lanka, December 02nd 2011.