Professor Nirmali Wickramaratne
Position: Professor
nirmaliw@med.sab.ac.lk
Office: +94-0452280013
Fax: +94-0452280013
Qualifications
Ph.D. in Biochemistry
Loyola University, Chicago
Chicago, Illinois USA
Graduate in Chemistry
Institute of Chemistry Ceylon Rajagiriya
Sri Lanka
Membership of Professional Bodies/Associations
Life Member, Sri Lanka Association for the Advancement of Science.
Life Member, Institute of Chemistry Ceylon
Research Interests
Protein -Drug Interaction (investigation on protein denaturation and Drug-Protein binding capacities under varying buffer conditions
Impact of energy balance and physical activity changes on body composition and physical fitness during the university years of Sports Sciences undergraduates in Sri Lanka
Preparation of Hydroxyapatite nano-composites for biomedical applications
Antioxidant and anti-diabetic activities of medicinally important plants in Sri Lanka
Genetic analysis of β Thalassemia mutations
Current Research Projects
Protein -Drug Interaction (investigation on protein denaturation and Drug-Protein binding capacities under varying buffer conditions
Impact of energy balance and physical activity changes on body composition and physical fitness during the university years of Sports Sciences undergraduates in Sri Lanka (Funded by Sabaragamuwa University Research Grant)
Preparation of Hydroxyapatite nano-composites for biomedical applications (Research Collaboration with Prof Yingchao Han ,Wuhan University of Technology China)
Antioxidant and anti-diabetic activities of medicinally important plants in Sri Lanka (With the Collaboration of Prof D.B. Mahinda Wickramaratne Faculty of Allied Health Sciences and Prof Lalith Jayasinghe Institute of Fundamental Studies Hanthana Kandy)
Recent Publications
Ultrasound-Assisted Synthesis and Characterization of Heparin-Coated Eu3+ Doped Hydroxyapatite Luminescent Nanoparticles Qingguo Xing, Xiaojun Zhang, Dulan Wu, Yingchao Han, M.Nirmali Wickramaratne Honglian Dai Xinyu Wang, Colloid and Interface Science Communications 29 (2019) 17–25
Controllable Synthesis of Poly(acrylic Acid)-Stabilized Nano-Hydroxyapatite Suspension by an Ultrasound-assisted Precipitation Method Dong Yan, Yuxin Lou, Yingchao Han, M. Nirmali Wickramaratne, Honglian Dai, Xinyu Wang 2018 Materials Letters: 4, 124 - 227
Influence of alginate fixation on the adsorption capacity of hydroxyapatite nanocrystals to Cu2+ ions, Jiali Guo, Yingchao Han, Yuting Mao, M. Nirmali Wickramaratne, Colloids and Surfaces A, 2017; 529, 801–807
Screening of edible plants in Sri Lanka for antioxidant activity. Chethana Galketiya T Sampath Weerarathna, J Chamini Punchihewa M Nirmali Wickramaratne and DBM Wickramaratne, Journal of Medicinal Plants Studies, 2017 5(1) 91-95
Hemoglobin Denaturation in the Presence of Chloroquine Phosphate. S. M. Soysa, M. Nirmali Wickramaratne. J Pharm Chem Biol Sci, 2016; 4 (4)
Contamination of Heavy Metals in Aquatic Vegetables Collected from Cultivation Sites in Sri Lanka. M. Nirmali Wickramaratne, L.L. Sanjaya, T. M. Maduranga IOSR Journal of Environmental Science, Toxicology and Food Technology, 2016, 10(11) 76-82
In-vitro alpha amylase inhibitory activity of the leaf extracts of Adenanthera pavonina,M. Nirmali Wickramaratne J. C. Punchihewa and D. B. M. Wickramaratne, BMC Complementary and Alternative Medicine 2016, 16; 466-471
Antioxidant Activity and Antibacterial Activity of Walidda antidysenterica. M. Nirmali Wickramaratne, L.P. Gunatilake, N.G. D. Anuradha, A.N. Godavillathanna, M.G.N. Perera, I. Nicholas., Journal of Pharmacognosy and Phytochemistry 2015; 4(2): 121-126
Rare Haemoglobin Varients Hb G Szuhu and Hb G Coushatta and Hb Mizuho in Sri Lankan families P.S. Perera, D.P.S.I. Silva, M. Hapugoda, M.N. Wickramaratne, I. Wijesiriwardena, D.G. Efremove, C.A. Fisher, D.J. Weatherall, Anuja Premawardhena Hemoglobin (2015) 39: 1 62-65
Completed Research Projects
Genetic analysis of β Thalassemia mutations (with the collaboration of Professor Sir David Weatherall of Weatherall Institute of Molecular Medicine at John Radcliffe Hospital, Oxford University and Prof. Anuja Permawardhena from University of Kelaniya Sri Lanka.)